<p>This entry represents rubredoxin-oxygen oxidoreductases. This includes enzymes such as the flavorubredoxin oxidoreductase NorV (or nitric oxide reductase flavorubredoxin) that contains one rubredoxin domain and binds FMN as a cofactror, acting to sense nitric oxide (NO) by formation of a mono-nitrosyl iron complex. NorV uses NADH to detoxify nitric oxide under anaerobic conditions, thereby protecting several 4Fe-4S NO-sensitive enzymes [<cite idref="PUB00042734"/>, <cite idref="PUB00042735"/>]. NorV has at least two reductase partners, one of which is NorW (flavorubredoxin reductase). NorV can also function as an aerobic oxygen reductase.</p><p>Other enzymes include the metalloflavoprotein FprA that functions as a low-potential electron donor to a number of redox enzymes [<cite idref="PUB00032624"/>]. There is also FpaA (flavoprotein A) that probably functions as an electron acceptor for a hydrogenase [<cite idref="PUB00042737"/>].</p> Rubredoxin-oxygen oxidoreductase